extending the debate on poor response to hepatitis b virus vaccination in children with celiac disease: which question remains?

Extending the Debate on Poor Response to Hepatitis B Virus Vaccination in Children With Celiac Disease: Which Question Remains?

A poorer response to hepatitis B vaccination, in coeliac subjects, compared to healthy subjects, has been largely debated. Almost all authors postulated that human leu-kocyte antigen (HLA) genotype DQ2, found in 90-95% of coeliac patients, could represent the main cause in determining the impaired antibody response to recombinant HBV vaccine (1), as well as observed also in healthy not responde...

Hepatitis B Vaccination Reliability in Celiac Disease

* Corresponding author at: Mohammad Rostami Nejad. Research Centers for Gastroenterology and Liver Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, IR Iran. Tel: +98-2122432518, Fax: +98-2122432517. Email: [email protected] DOI: 10.5812/kowsar.1735143X.761 Copyright c 2011, BRCGL, Published by Kowsar M.P.Co. All rights reserved. c 2011 Kowsar M.P.Co. All rights reserved. Pl...

hepatitis b vaccination reliability in celiac disease

Hepatitis B virus and celiac disease

Regarding the article of Leonardi and La Rosa: "Are hepatitis B virus and celiac disease linked?", published in the 2010 issue of Hepatitis Monthly (1), we believe that there is no relationship between the hepatitis B virus (HBV) and celiac disease (CD). None of the study’s patients tested positive for immunoglobulin A anti-endomysium or immunoglobulin A anti-tissue transglutaminase antibodies,...

Celiac disease and hepatitis B virus

We read with interest the article by Leonardi and La Rosa (2010) that deals with the hypothesis that nonintestinal inflammatory diseases, such as hepatitis B virus (HBV), may trigger immunologic gluten intolerance in susceptible people (1). A recent study indicated that a high frequency of rotavirus infections may increase the risk of celiac disease (CD) autoimmunity in genetically predisposed ...

Evaluation of the response to vaccination with hepatitis B vaccine in pediatric patients diagnosed with celiac disease

BACKGROUND A gap exists in the literature on celiac disease populations and the response to hepatitis B vaccination. OBJECTIVE To identify pediatric patients with celiac disease who received the primary hepatitis B vaccination and investigate their response to vaccine. DESIGN/METHODS Patients underwent blood draw for hepatitis B surface antibody titers. Patients with undetectable or non-pro...